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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STAT5A All Species: 22.42
Human Site: Y683 Identified Species: 49.33
UniProt: P42229 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42229 NP_003143.2 794 90647 Y683 D E V F S K Y Y T P V L A K A
Chimpanzee Pan troglodytes XP_001165762 794 90647 Y683 D E V F S K Y Y T P V L A K A
Rhesus Macaque Macaca mulatta XP_001109557 794 90645 Y683 D E V F S K Y Y T P V L A K A
Dog Lupus familis XP_548091 794 90625 Y683 D E V F S K Y Y T P V F A K A
Cat Felis silvestris
Mouse Mus musculus P42230 793 90813 Y683 D E V F A K Y Y T P V L A K A
Rat Rattus norvegicus Q62771 793 90815 Y683 D E V F A K Y Y T P V L A K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q6DV79 771 88152 P603 A I L S T K P P G T F L L R F
Frog Xenopus laevis Q7ZXK3 766 87581 P603 A L L S P K P P G T F L L R F
Zebra Danio Brachydanio rerio NP_919368 785 89465 A661 D F S I R S L A D R I S D L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24151 761 86396 A649 N G L V T M L A P W T A R D F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NAD6 706 80563 M567 P A I D K E E M L R F F E S E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.6 96.8 N.A. 96.3 95.8 N.A. N.A. 28.9 28.9 77.4 N.A. 31.3 N.A. 24.6 N.A.
Protein Similarity: 100 100 98.9 98.6 N.A. 98.1 97.8 N.A. N.A. 48.3 49.2 87.4 N.A. 48.1 N.A. 43.5 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 13.3 13.3 6.6 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 33.3 26.6 13.3 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 0 0 19 0 0 19 0 0 0 10 55 0 55 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 64 0 0 10 0 0 0 0 10 0 0 0 10 10 0 % D
% Glu: 0 55 0 0 0 10 10 0 0 0 0 0 10 0 10 % E
% Phe: 0 10 0 55 0 0 0 0 0 0 28 19 0 0 28 % F
% Gly: 0 10 0 0 0 0 0 0 19 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 10 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 10 73 0 0 0 0 0 0 0 55 0 % K
% Leu: 0 10 28 0 0 0 19 0 10 0 0 64 19 10 0 % L
% Met: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 10 0 0 0 10 0 19 19 10 55 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 19 0 0 10 19 0 % R
% Ser: 0 0 10 19 37 10 0 0 0 0 0 10 0 10 0 % S
% Thr: 0 0 0 0 19 0 0 0 55 19 10 0 0 0 0 % T
% Val: 0 0 55 10 0 0 0 0 0 0 55 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 55 55 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _